의약물질의 환경위해성 관리방안 연구
- Contents -
FOREWORD
Abstract
Acronym List
Chapter 1. Introduction
Chapter 2. Review and Background
1. Occurrence Studies of Pharmaceuticals in the Korean Aquatic Environment
2. Environmental Safety Regulations for Pharmaceuticals
2.1The European Union
2.2The United States
2.3Canada
2.4Australia
2.5Japan
3. Models for Predicting PECs of Pharmaceuticals
3.1Models for Predicting PECs of Human Pharmaceuticals
3.2Models for Predicting PECs of Veterinary Pharmaceuticals
3.3Selecting Models for This Study
Chapter 3. Exposure Simulation for Human Pharmaceuticals in the Han River with PhATETM
1. Constructing PhATETM for the Han River
1.1Watershed Data for the Han River
1.2Target Compounds and Collection of Compound-Specific Data
2. Modeling Human Pharmaceuticals in the Han River Watershed with PhATETM
3. Point-by-Point Comparisons of Model Data to Field Data
3.1Field Measurement Data
3.2Point-by-Point Comparisons
Chapter 4. Predicting Environmental Exposure of Veterinary Pharmaceuticals with SWMM model in the Kyungahn Stream
1. Introduction
2. Materials and Methods
2.1Study Area
2.2Selection of Target Pharmaceuticals
2.3Application of SWMM
3. Results and Discussion
3.1Simulation of Runoff Flowrate
3.2Simulation of Runoff Quality
4. Conclusions
Chapter 5. Environmental Exposure Modeling of Pharmaceuticals with the PhATETM-SWMM Combined Model in the Kyungahn Stream
1. Materials and Methods
1.1Target Pharmaceuticals
1.2Model Application
2. Results
2.1PhATETM model in the Kyungahn stream
2.2Integrated Concentration of Sulfamethoxazole and Trimethoprim
Chapter 6. Environmental Risk Assessment for Selected Pharmaceuticals
1. Introduction
2. Materials and Methods
2.1Daphnia Chronic Test
2.2Fish Test
2.3Risk Assessment
3. Results and Discussion
3.1Daphnia Test
3.2Fish Test
3.3Risk Assessment
4. Conclusions
Chapter 7. Summary and Conclusions
1. Summary of This Study
2. Suggested Potential Risk Management Actions
References
Appendix 1: PhATETM Input Data in the Han River
Appendix 2: SWMM Model Verification Data
Abstract in Korean
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