환경위해성 평가를 위한 기초자료 확립과 심사사례 분석
I. Introduction 18
1. Background 18
2. Objectives 19
3. Materials and Methods 20
II. Status of field Test and Commercialization of LMO 22
1. Field Test: Global Status 22
2. Field Test: Major countries 24
2.1 United States of America 24
2.1.1 Genetically Modified Crops 24
2.1.2 Genetically Modified Microorganisms 28
2.1.3 Genetically Modified Insect 29
2.2 Canada 30
2.3 Europe 31
3. Commercialization 35
3.1 Global Status 35
3.2 Korea 40
III. Case study: Risk Assessment of Genetically Modified Microorganism 42
1. Review of Current Case Study 42
2. Risk Assessment of Geneically Modified Rhizobium leguminosaum with Activated β-glucuronidase 46
2.1. Rhizobium 46
2.2. Procedure of Risk Assessment of United Kingdom 47
2.2.1 Application 50
2.2.2 Field Test and Report after Approval 52
2.3. Official Document of Environmental Risk Assessment 53
2.4. Review of Risk Assessment Application by Government of United Kingdom 57
2.5. Discussion 62
IV. Management of Database 63
1. OECD 63
1.1 Biosafety 63
1.2 Information Sharing 64
1.3 Field Test and Product Data 66
2. Europe Union 69
3. United States of America 75
3.1 Database of Field Test 76
3.1.1 USDA/APHIS 76
3.1.2 EPA 80
4. Canada 82
5. Korea 85
V. Case Study on Environmental Risk Assessment Model of LMO 87
1. Concept of Environmental Risk Assessment of LMO 87
2. Case Study 88
2.1 Edmonds Institute 89
2.2 Dtree 92
2.2.1 Comprehensive Risk Assessment of Genetically Modified Crop 94
2.2.2 Environmental Risk Assessment of Herbicide Resistant Crop 98
2.3 Risk Assessment Searching Mechanism of ICGEB 99
2.4. Analysis of Existent Models 102
VI. Construction of Pilot Website 104
1. Introduction 104
2. Contents and Construction 105
2.1 Information Center for Risk Assessment of LMO 105
2.2 Environmental Risk Assessment of LMO 106
2.3 Biosafety Protocol 107
2.4 Reference of Environmental Risk Assessment of LMO 108
2.5 Status of LMO Products 110
3. Environmental Risk Assessment System of LMO 112
3.1 Introduction 112
3.2 Constitution and Logic of Risk Assessment System 113
3.2.1 Comprehensive Risk Assessment System 113
3.2.2 Environmental Risk Assessment System of LMO 117
3.3 Feature and Limitation of Risk Assessment System 127
4. Improvement and Management of Website 132
VII. Conclusion 133
Abbreviation 136
Reference 138
Appendix 142
Appendix 1. List of LMO Products 142
Appendix 2. Field Test Data of Europe Union 147
Appendix 3. Field Test Data of Canada 149
Appendix 4. Field Test Data of Genetically Modified Microorganisms of Unites States 152
Appendix 5. Result of Dtree's Comprehensive Risk Assessment 180
Appendix 6. Biology of Major Genetically Modified Crop 186
6.1 Soybean 186
6.2 Corn 194
6.3 Rice 206
6.4 Potato 215
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